The market for Soft Gelatin Capsules (SGCs) has skyrocketed in the last few years, subsequently leading to an increase in the demand for pharmaceutical softgel capsules manufacturers. Third-party manufacturing companies facilitate businesses that have a product vision but lack the manufacturing capabilities to actualize that vision. This enables the latter to focus on their core competencies while leaving the production aspect of the business to experts.
There are many reasons Soft Gelatin Capsules (SGCs) have captured the interest of aspiring pharma business owners. Firstly, these are widely accepted in the pharma industry due to their proven safety profile. They are solid dosage forms containing one more APIs (Active Pharmaceutical Ingredients) or nutrients, which are suspended, dispersed, or dissolved in a liquid/semisolid fill, and covered within an elastic gelatin shell. ‘Gelatin’ not only has non-allergic properties, but also contains proteins which are easy to swallow and digest. But since Gelatin is also temperature and moisture sensitive, manufacturing of SGCs can be challenging. This is another reason pharma businesses often turn to an experienced soft gelatin capsules manufacturer to meet their production needs.
Given below are some critical insights about Soft Gelatin Capsule manufacturing that every pharma franchise business planning to outsource their manufacturing requirements should know.
Shell Material Preparation
The manufacturing process begins with preparing the shell for the capsules that will contain the fill material and protect it from external environment factors, like humidity, fluctuating temperature, etc. The composition of the shell typically includes gelatin, water, plasticizer, and other ingredients like coloring, sugars, opacifying agents, etc. To get the perfect shell for Soft Gelatin Capsules, all these ingredients are mixed in a gelatin melting tank at an appropriate temperature. The process results in a gel mass which is used for making shells for the capsules.
Fill Material Preparation
Fill materials for soft gelatin capsules come in various forms, like liquids, semi-solids, or suspensions. These materials are milled and mixed in a specialized processing tank to get a fill mass, which, if required, is made to go through vacuum for removing air bubbles.
In order to maintain the quality and efficacy of softgel capsules, it is important that the fill material used in them meets the given criteria:
- Guarantee stability of all individual elements, including the active ingredients.
- Increase bioavailability, a major reason why softgel capsules are popular.
- Ensure efficient and safe filling process.
- Ensure that fully filled Soft Gelatin Capsules remain stable.
The Encapsulation Process
Today, most Pharmaceutical softgel capsules manufacturers use the rotary die encapsulation process for producing Soft Gelatin Capsules. The method entails using rotating die rolls in order to form gelatin shells or containers, inject the fill material in them, and then seal the capsules properly. The rotary die encapsulation process is widely used for softgel capsule manufacturing as it ensures consistent quality and high production rates.
For best results, it is important to invest in a quality softgel encapsulation machine, which –
- Adheres to the Current Good Manufacturing Practice (CGMP) regulations
- Has the right specifications and features to meet your specific production requirements
- Is easy to operate and maintain
- Features a robust automation system and control panel
After encapsulation, the Soft Gelatin Capsules fall into a conveyor that moves them towards the next step i.e. drying. During this step, the capsules are put in a tumble dryer by the conveyor for removing excess moisture from them. This is followed by steps like inspecting, sorting, cleaning, and polishing.
Cista Medicorp – The Most Trusted Soft Gelatin Capsules Manufacturer in India
Established over 20 years ago, Cista Medicorp is the most trusted soft gelatin capsules manufacturer in India today. As an ISO-approved pharmaceutical manufacturing company, we follow the most stringent quality standards to ensure the safety and reliability of our pharma products. In our wide range of soft gelatin capsules, you can find Algamin, Calamol, Calcilyf K27, Callum D3, Co-Lyf, Grossvit 12G, NurotalPlus, Rosipep, and various other capsules. What makes our pharma products stand out is that they are made of 100% safe and clean ingredients that are sourced from the most trusted vendors in the country.
To learn more, feel free to call @ +91-7508340032 or email @ cistamedicorp@gmail.com.
Frequently Asked Questions
Q. What sizes of soft gelatin capsules do you offer?
A. We offer soft gelatin capsules in a variety of sizes, ranging from small to large, for accommodating various fill volumes and dosages.
Q. Is there any minimum order quantity for soft gelatin capsule manufacturing?
A. Yes, we do have minimum order quantity that typically depends on factors, such as product formulation, customization requirements, etc. For more details, feel free to contact us.